| ncRNA name | hsa-miR-675-5p |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | human lens epithelium samples |
| Methods | qRT-PCR, transfection, MTT assay, Calcein-AM and proPIdium iodide double staining, Rhodamine 123 and Hoechst double staining, EdU incorporation assay, transwell assay, luciferase reporter assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-675 regulates CRYAA expression by targeting the binding site within the 3'UTR. miR-675 increases the proliferation and migration while decreasing the apoptosis of HLECs upon oxidative stress. |
| PubMed ID | 30286462 |
| Year | 2018 |
| Title | Long Non-Coding RNA H19 Regulates Human Lens Epithelial Cells Function. |
| Drug-related ncRNA | NO |
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